Fecal Transplantation: A Powerful Therapy for Recurrent C. Difficile

By May 1, 2015Pharma Beat
Fecal Transplantation

Clostridium difficile (C. Difficile), a bacterium that causes diarrhea and intestinal conditions, is the most frequent cause of infectious diarrhea in hospitals and long-term care facilities. The elderly, people with severe underlying illness or those requiring long-term treatment with antibiotics are at higher risk for the infection. Although C. Difficile is typically treated with antibiotics, recurrence occurs in approximately 25% of patients.

Gaining interest over the past few years is the use of fecal transplants for the treatment of recurrent C. Difficile. Fecal transplantation involves the transfer of purified donor fecal matter into the infected patient through colonoscopy.  Greater than 90% cure rates have been reported using this procedure.

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