Cheers to Improved Cardiometabolic Risk Markers!

By October 16, 2015Blog Posts, Pharma Beat

This past Thanksgiving weekend was a weekend filled with family, turkey, stuffing, potatoes, and perhaps, a glass of wine with dinner. For those Canadians with type 2 diabetes mellitus (T2DM) there is good news: that glass of wine may improve their lipid and glycemic profile.

Results of the Cardiovascular Diabetes and Ethanol trial (CASCADE) were published October 13 in the Annals of Internal Medicine. In the study 224 patients from two centres in Israel were placed on a healthy Mediterranean diet and randomized to 150 mL of red wine, white wine or mineral water per day. After 2 years, those in the red wine group had significantly higher levels of HDL and apolipoprotein (the primary outcomes) compared with the water group.

The results are somewhat controversial because the study was a small study and investigated surrogate markers for morbidity and mortality. However, the results seem to suggest a glass of wine with dinner could have beneficial effects for patients with T2DM.