BP Lowering in Type 2 Diabetes Reduces Deaths, CVD Outcomes

By February 20, 2015Pharma Beat
MEDUCOM BP Lowering in Type 2 Diabetes

Patients with diabetes are more likely to have high blood pressure (BP) than those without. In these patients, high BP greatly increases the risk of developing macrovascular/microvascular complications of diabetes and premature death.

This week, Emdin et al. published a meta-analysis on the impact of BP lowering in patients with type 2 diabetes, which represents the most detailed analysis on the subject to date. Using data from 100 354 patients enrolled in 40 trials, they showed a 10-mm-Hg reduction in systolic BP was associated with an 11% to 17% lower relative risk of death, cardiovascular events, heart disease, retinopathy, and albuminuria and a 27% lower relative risk of stroke. The full article can be found in this week’s issue of JAMA (http://bit.ly/1zTAcXY).

The ideal BP target for patients with diabetes remains a controversial issue, with no worldwide consensus. The results of this meta-analysis support the current Canadian Hypertension Education Program (CHEP) guidelines which recommend a lower BP target of <130/80 mm Hg in hypertensive patients with diabetes.

Courtney